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Trends of blood pressure in patients with acute myocardial infarction combined with chronic kidney disease |
Li Hong-yan, Wang Long-an, Li Jing-yu |
Department of Emergency, Henan Province People′s Hospital, Zhengzhou 450003, China |
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Abstract Objective To investigate the trends of blood pressure in patients with acute myocardial infarction (AMI) combined with chronic kidney disease (CKD). Methods AMI combined with CKD patients of stage 3, 4 and 5 were consecutively recruited from a single center (n=324). Based on office measured systolic blood pressure (SBP) and diastolic blood pressure (DBP), they were classified into any of the four hypertensive subtypes: normotension (SBP/DBP<140/90 mm Hg), isolated diastolic hypertension (IDH, SBP<140 mm Hg, DBP≥90 mm Hg), ISH (SBP≥140 mm Hg, DBP<90 mm Hg) and systolic-diastolic hypertension (SDH, SBP/DBP≥140/90 mm Hg). Results The overall control rate of hypertension was 45.7%, with decreased control rate relative to advanced CKD stages. The prevalence of IDH changed from 5.0% to 5.3% and 0 from stage 3 to 4 and 5, while no significant change in the prevalence of SDH was observed (15.0%, 14.9% and 15.7% in stage 3, 4 and 5, respectively). There was a stepwise increase in the prevalence of ISH with the stages of CKD (it was 28.1%, 39.4% and 45.7% in stage 3, 4 and 5, respectively). Logistic regression analysis showed that age and CKD stages (compared with stage 3, stage 4 and 5 had 2.13 and 3.99 folds higher risk to develop ISH, respectively) were independent predictors of ISH in these patients. Conclusion〓 The prevalence of ISH increases correspondingly with the advanced stages of CKD, and more advanced CKD stage are associated with increased risk to develop ISH, which may partially contribute to increased cardiovascular mortality during the progress of CKD.
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Corresponding Authors:
Li Jing-yu, E-mail: hyli335@163.com
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