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| Evaluation of prognosis in patients with cardiopulmonary resuscitation by BIS and lactate clearancerate |
| Wang Shu-mei, Zhang He-wei, Ran Yu |
| Zhu Xianyi Memorial Hospital of Tianjin Medical University, Tianjin 300134, China |
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Abstract Objective To investigate the bispectral index (BIS) combined with lactate clearance rate to assess the value of neurological prognosis. Methods Patients with coma who underwent cardiac arrest after cardiac arrest were successfully monitored for BIS, and GCS scores, 24-hour lactate clearance was calculated, 6-month prognosis was observed, and correlations among the three were analyzed. The statistical difference between the prognosis and the target group before and after the target temperature management was compared, and the ROC curve was analyzed. Results The BIS value and GCS score after target temperature management were higher than before. BIS value was positively correlated with GCS score and lactate clearance rate (r=0.902, 0.631, P<0.001). There was a significant difference in BIS and lactate clearance between the prognosis of neurological function and poor prognosis after target temperature management ［72.57±8.28 vs. 51.43±9.66, (58.69±5.74)% vs.(42.91±8.52)%, P＜0.05］. The BIS value and lactate clearance rate after target temperature management were better than GCS score (AUC =0.989, 0.935, 0.890, P＜0.001). The BIS value greater than 58.5 and lactic acid clearance rate greater than 54.5% are the best predicted points to the good prognosis of patients with CPR. Conclusion〓 BIS is an effective index to evaluate the degree of coma after target temperature management and to determine the prognosis of neurological function after cardiopulmonary resuscitation. In terms of prognosis, objective indicators of BIS and lactate clearance are superior to subjective indicators GCS score.
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Corresponding Authors:
Ran Yu, E-mail: 1306641703@qq.com
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