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| Changes and monitoring of microcirculation and vascular reactivity in septic shock |
| YUAN Hui-qin, LIU Li-jun |
| ICU, the Second Affiliated Hospital, Soochow University, Suzhou 215000, China |
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Abstract Shock is an acute circulation failure caused by a variety of strong pathogenic factors in the body. The characteristic is that the microcirculation perfusion is insufficient, which leads to the systemic pathological process of cell metabolism and cell damage. The hemodynamic changes of various types of shock are not the same. According to the classification of hemodynamics, there are: low cardiac output and high resistance, high cardiac output and low resistance, low cardiac output and low resis⁃ tance. Of three types, high cardiac output and low resistance is the most common; the most common fea⁃ ture is the lack of microcirculation perfusion. According to the treatment strategy based on shock, there are: hypovolemic, cardiogenic, distribution and obstructive shock. Distribution shock is often one of the common causes of the patient's transfer to the intensive care unit（ICU）and high mortality in ICU. In the study of pathophysiological mechanism of shock, circulatory dysfunction is an important cause of tis⁃ sue perfusion. The vascular paralysis of septic shock is the main cause of circulatory dysfunction. In this paper, we reviewed the changes and monitoring of microcirculation and vessel reactivity in septic shock.
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Received: 26 January 2016
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Corresponding Authors:
LIU Li-jun, E-mail:Lijunliusz@sina.com
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