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| Analysis of prognostic factors in ICU patients with septic shock by multiple Logistic regression model |
| DAI Liang-cheng，SONG Fei，RU Huang-yao，WU Hao，WANG Su-ning，LAO Zhi-gang |
| ICU，the First Hospital Affiliated to Guangdong College of Pharmacy，Guangzhou 510080，China |
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Abstract Objective To investigate the prognostic factors in patients with septic shock in ICU. Methods The clinical data of 200 patients with septic shock in our hospital from July 2007 to July 2015 were retrospectively analyzed，including 68 patients death and 132 patients non death. First of all, the relevant data of the two groups were collected and analyzed，and then the correlation factors of the prognosis of patients with ICU were determined by single factor and multiple factor analysis. Results ①The differences in age, APACHEⅡ score, complication（Fungus infection, ARDS, DIC, AKI），throm⁃ bocytopenia, anticoagulant therapy were statistically significant（P＜0.05）by Pearson single factor analysis. ② The related factors were analyzed by Logistic Regression Model, showing that age（OR 2.502, 95% CI 1.392~4.430, P＝0.023），APACHEⅡ scores＞20（OR 2.129, 95% CI 1.188～4.732， P＝0.029），combined Fungus infection（OR 3.092, 95% CI 1.335～6.731, P＝0.029），combined ARDS （OR 2.627, 95% CI 1.297～5.032, P＝0.011）, combined AKI（OR 3.829，95% CI 1.615~5.592, P＝ 0.001），anticoagulant therapy（OR 0.293，95% CI 0.140～0.627, P＝0.001）. Conclusion There are many factors that affect the prognosis of patients with septic shock in patients with ICU，and these factors should be carefully observed，so as to take preventive measures to effectively improve the prognosis of patients.
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Received: 25 January 2016
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