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Clinical and prognostic factors of spontaneous intracerebral hemorrhage in children treated with PICU |
Feng Ai-ping, Wang Wen, Du Chen, Qiao Wei, Huang Qi-jun |
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Abstract Objective To evaluate the clinical and prognostic factors of spontaneous intracerebral hemorrhage (sICH) in children with pediatric intensive care unit (PICU) in the Second People′ Hospital of Deyang City. Methods The clinical data of 123 children under 14 years of age in PICU were included. The clinical characteristics and treatment methods of the children were evaluated. A univariate analysis and a COX multivariable proportional model analysis were used to evaluate the related factors of death in children, and the related factors that affect the prognosis of children with survival were evaluated too. Results The Admission glasgow coma score (GCS) was (7.45±3.10). The most important pathogenicity of sICH was arteriovenous malformation (35.8%, 44/123). The total mortality rate of children was 24.4% (30/123). COX multivariable proportional model analysis showed that the midline shift was positively correlated with the death rate of children (HR=5.731, 95%CI1.869~17.574, P=0.003). The lower admission GCS score (HR=3.248, 95%CI1.556~6.778, P=0.003) was significantly associated with poor prognosis in the survival of PICU. Conclusion sICH is a serious disease which seriously affects the safety and health of the children. The main cause of the disease was sudden rupture of arteriovenous malformation. The midline shift and the admission GCS were important factors affecting the survival rate and the prognosis of the children.
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About author:: Feng Ai-ping, E-mail: jackfengap@sina.com |
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