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| The value of peripheral blood lymphocyte-neutrophil ratio in the diagnosis of complicated acute appendicitis |
| Sun Yu-jia, Liu Si, Gao Yu-song, Wang Bo, Xiong Hui |
| Department of Emergency, Peking University First Hospital, Beijing 100034, China |
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Abstract Objective This study aims at identifying the relationship between the routine blood test features and the severity of acute appendicitis to provide guidance for conservative treatment. Methods A retrospective clinical analysis was made on 179 appendectomy patients with acute appendicitis in Peking University First Hospital. According to pathology reports of all cases, the initial preoperative blood routine examination results were statistically evaluated at different stages of acute appendicitis (uncomplicated acute appendicitis vs. complicated acute appendicitis). Results 179 patients of acute appendicitis included 85 patients (47.49%) with uncomplicated acute appendicitis (UAA) and 94 patients (52.51%) with complicated acute appendicitis (CAA). Statistical analysis indicates that patients with CAA have significant decreases compared with UAA in the lymphocyte count(LY)［ (1.53±1.03)×109 /L vs. (1.10±0.65)×109 /L, P=0.001］ and lower rates of the lymphocyte percentage(LY%)［(12.56±7.72）% vs.（7.80±4.87）%, P=0.000］and lymphocyte-neutrophil ratio(LNR%) ［(17.69±15.95)% vs. (9.45±7.43)%, P=0.000］. Conclusion LY,LY% and LNR% can be useful to evaluate the severity of acute appendicitis.
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Corresponding Authors:
Liu Si, E-mail: docleo@vip.sina.com
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