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| Analysis of prognostic factors in ED patients with sepsis |
| Lv Jun-hua, Shi Yu, Wang Dan, Pei Hong-hong, Wang Hai |
| The Second Affiliated Hospital of Xi′an Jiaotong University, Xi′an 710004, China |
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Abstract Objective To explore the related factors influencing the 28-day survival rate of sepsis in the emergency department based on an open database. Methods A retrospective case-control study was done to analyze the related factors of patients who underwent sepsis in ED from January 2017 to April 2018. Results A total of 302 cases were included in the study and were divided into survival group (n=238) and death group (n=64) according to the prognosis of 28 days. Univariate analysis revealed that age, peak pulse, respiratory frequency, mean arterial pressure, SOFA, qSOFA, APACHE Ⅱ scores, biochemical and coagulation-related parameters, and treatment related to prognosis, the difference was statistically significant between the surviving and death groups. The survival group had a lower age (58.36±20.19) than the death group (68.03±17.49) years, P=0.317. The length of stay in the survival group was (14.97±10.98) was higher than that in the death group (6.03±7.23) (P<0.001). Multivariate logistic regression analysis showed that SOFA scores, length of study were related to the 28-day survival. The OR values were 0.89 (0.82, 0.96) and 1.40 (1.22, 1.59), respectively. ROC curve analysis showed that the SOFA score had a high predictive value for the 28-day survival rate of sepsis. The ROC area was 0.84 (0.78, 0.90), the critical value was 8 points, the sensitivity was 72%, and the specificity was 83%. Conclusion Patients with sepsis have a serious condition and poor prognosis. SOFA score is a reliable indicator to predict prognosis. In the course of diagnosis and treatment, patients should be continuously evaluated for changes in condition and the patient should be given the most suitable diagnosis and treatment.
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Corresponding Authors:
Wang Hai, E-mail: 470050727@qq.com
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