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| Study on the improvement of gastrointestinal dysfunction in sepsis patients treated with routine western medicine combined with rhubarb and aconite decoction |
| Yang Chao, Wang Yu-zhen, Bai Kui, Zhang Er-hui, Gao Hai-bo |
| Intensive Care Unit, First Affiliated Hospital of Henan University, Zhengzhou 475000, China |
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Abstract Objective To explore the effect of routine western medicine combined with Dahuang Fuzi decoction on gastrointestinal dysfunction in sepsis patients. Methods 140 patients with sepsis admitted in our hospital from January 2017 to December 2017 were divided into experimental group and control group according to the different treatment methods. The control group was treated with routine western medicine. The experimental group was treated with routine western medicine combined with rhubarb aconite decoction, and the improvement effect of routine dysfunction was observed in both groups. Results There was no significant difference in plasma D-lactic acid levels between the two groups before treatment and 1 day after treatment(P>0.05), while that in control group was significantly lower than that in control group at 7 and 14 days after treatment (nmol/L:0.13±0.01 vs.0.18±0.02,0.09±0.01 vs. 0.17±0.01, P<0.05). The improvement of gastrointestinal dysfunction score(score:1.53±0.26 vs.1.13±0.28) and APACHEⅡ score(score:11.26±2.67 vs.8.54±2.58) in the experimental group was significantly better than that in the control group (P<0.05), the difference was statistically significant (P<0.05). Conclusion In the course of treating sepsis patients, the main direction is to improve the gastrointestinal function of patients. On the basis of routine western medicine treatment, rhubarb aconite decoction can improve gastrointestinal function by regulating plasma D-lactic acid concentration in patients.
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| About author:: Yang Chao, E-mail: nnmb0625@126.com |
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