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| Early reperfusion therapy and in-hospital mortality in octogenarian patients with ST-segment elevation myocardial infarction in Henan province |
| Zhang You, Gao Chuan-yu, Duan Guang-cai, Liu Xin-yun, Wang Xian-pei, Li Mu-wei, Qi Da-tun, Hu Da-yi |
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Abstract Objective To assess the early reperfusion therapy and in-hospital mortality in octogenarian patients with ST-segment elevation myocardial infarction (STEMI) in Henan province. Methods Data was collected from 1633 patients with STEMI enrolled in 17 hospitals in Henan, from June 2011 to June 2012, and was divided into two groups: octogenarian group (age≥80 years;n=126) and younger group (age<80 years; n＝1507). Patient characteristics, management strategy, pharmacological treatments during the admission, in-hospital mortality and bleeding complications were compared between the two groups. Results Octogenarian patients were more female, and with higher proportion of cardiac dysfunction, prior ischemic stroke and prior angina, but lower rate of dyslipidemia and smoking. Compared with younger patients, octogenarian patients had a lower proportion of early reperfusion therapy (P<0.05), especially thrombolysis therapy (P<0.05). The use of primary percutaneous coronary intervention (PCI) was similar between octogenarian and younger groups (P>0.05). There was no difference in the successful rate of early reperfusion or time from symptom onset to reperfusion between two groups (P>0.05). Octogenarian patients had a shorter duration of hospital stay and higher in-hospital mortality (P<0.05). Age ≥80 years was an independent risk factor of in-hospital death. Conclusion Octogenarian patients have a lower proportion of early reperfusion therapy and higher in-hospital mortality.
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Received: 03 March 2017
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