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| Analysis of the factors that affect the prognosis of the 272 patients with acute paraquat poisoning |
| Meng Zhao-hua, Su Xiao-yun, Gong Yu, Xiao Hao, Gao Heng-bo, Tian Ying-ping, Yao Dong-qi |
| Emergency Department, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China |
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Abstract Objective This investigation will analyze the early factors that affect the prognosis ofacute paraquat poisoning, and provide basis for clinical treatment plan adjustment, in order to reduce the mortality rate and the financial burden of paraquat poisoning patients. Methods Between December 2011 to December 2014, 272 patients with paraquat poisoning were selected from the Department of Emergency Medicine of Second Hospital of Hebei Medical University. We registered the gender, age, taking poison quantity, drinking or not, poison-concentration, and detected WBC, CK-MB, LDH, ALT, AST, potassium, AG, CO2, Cr, BUN, GLU, AMY, ALB, Na, Ca, PT, APTT, etc within 1 hour after admission. According to the prognosis within 30 days, they were divided into two groups, survival group and death group.Statistical analysis was carried out by two steps: the single factor and multiple factors analysis. Relationship between these indexes and the prognosis of patients was tested by binary logistic regression analysis step by step back（Backward: LR）. The result was different significantly if P＜0.05. Results For patients with paraquat poisoning, there were statistical differences in drink status, taking poison quantity,WBC, CK-MB, LDH, ALT, AST, K +, AG, CO2, Cr, BUN, GLU, AMY（P＜0.05）between survival groupand death group. However, gender, ALB, Na+, Ca2+, PT, APTT, had no statistical differences（P＞0.05）.The Logistic regression analysis indicated that the taking poison quantity, poison concentration, drink status, WBC, CK-MB, ALT, K +, Cr, Glu are independent risk factors of early prognosis of acute paraquat poisoning（P＜0.05）. Conclusion There are statistical differences in drink status, taking poison quantity, poison, WBC, CK-MB, LDH, ALT, AST, K +, AG, CO2, Cr, BUN, GLU, AMY in survival group and death group for patients with paraquat poisoning. The taking poison quantity, poison concentration,drink or not, WBC, CK-MB, ALT, K +, Cr, Glu are independent risk factors of early prognosis of acute paraquat poisoning.
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Received: 13 November 2016
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Corresponding Authors:
Tian Ying-ping, E－mail: tianyingping－jzh@163.com
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Address: 1 North 2nd Street,
Zhongguancun, 
