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| The effect of blood pressure during resuscitation on the short term outcome of patients suffered
from cardiac arrest |
| XING Xue-zhong, WANG Hai-jun, QU Shi-ning, ZHANG Hao, HUANG Chu-lin,WANG Hao, YANG Quan-hui, GAO Yong |
| Intensive Care Unit, National Cancer Center/Cancer Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China |
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Abstract Objective To investigate the effect of blood pressure during resuscitation on the short term outcome of patients suffered from cardiac arrest. Methods Data of 19 patients with cardiac arrest who admitted to Intensive Care Unit of Cancer Hospital of Chinese Academy of Medical Sciences from January 2011 to September 2015 were retrospectively collected and analyzed. Results Three patients withdrew and 16 patients received resuscitation. There were 11 males and 5 females with a mean age of 57 years. Of 16 patients, 8 patients died within 24 hours after admission and 8 patients survived.Univariable analysis demonstrated that patients died within 24 hours were more severe as reflected by sequential organ failure assessment (SOFA) score (13±2 vs. 8±5, P＝0.037), and they had more hypotension (75% vs. 12.5% ，P＝0.012), received more dosage of epinephrine [(5 ± 4) mg vs. (2 ± 2) mg，P＝0.043] and had lower mean blood pressure [(57±14) mm Hg vs. (76±11) mm Hg，P＝0.008]compared with patients survived. Receiver operating curve analysis showed that the cutoff value of MAP during resuscitation in predicting the survival within 24 hours was 62 mm Hg, with a sensitivity of 100%, and a specificity of 75% (area under the curve was 0.883±0.088，95% confidential interval: 0.711~1.055，P＝0.010). Patients with MAP greater than 62 mm Hg had no improvement in cerebral performance category on discharge, but lower in-hospital mortality (50% vs. 100%，P＝0.037) compared with patients whose MAP was less than 62 mm Hg. Conclusion For patients suffered cardiac arrest, maintaining MAP level greater than 62 mm Hg during resuscitation may improve the 24 hour survival and in-hospital mortality,but not cerebral performance category.
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Received: 10 November 2015
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Corresponding Authors:
GAO Yong, E-mail: 2354839907@qq.com
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