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Analysis on the predictive factors of heart failure after recanalization of IRA for AMI patients
with preserved systolic function of left ventricle |
XU Jia-liang, LIU Ming, HE Zhi-song, CHENG Xu-jie, JIANG Ting-bo |
Department of Cardiology, the First Affiliated Hospital of Soochow University, Su?zhou 215006, China |
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Abstract Objective To investigate the risk and predictive factors for the occurrence of heart failure after recanalization of infarct- related artery (IRA) during percutaneous coronary intervention(PCI) for acute myocardial infarction (AMI) patients with preserved systolic function of left ventricle.Methods 413 AMI patients with preserved ejection fraction who were treated by the PCI from January 2013 to April 2015 in hospital were divided into heart failure group and control group, and their clinical
data were statistically analyzed. Risk factors related to heart failure were analyzed by multifactorial logistic regression analysis and the predicted effect was determined by ROC curve. Results ①The heart failure of AMI patients with preserved systolic function of left ventricle was positively associated with left atrial diameter, women, the infarct artery of left main coronary artery or left anterior descending branch,proximal vessel infarction, multi-vessel lesion, neutrophil, hs-CRP, LVS, vascular opening time and history of hypertension, where the difference between groups was statistically significant (P<0.05). ② Mul⁃tifactorial logistic regression analysis showed that women, the infarct artery of left main coronary artery or left anterior descending branch, proximal vessel infarction, multi-vessel lesion, neutrophil, hs-CRP, vascular opening time and history of hypertension were independent predictors of heart failure. ROC curve analysis for this prediction model showed that the area under the curve was 0.783 (95%CI 0.739~0.828,P<0.001). Conclusion Women, the infarct artery of left main coronary artery or left anterior descending branch, proximal vessel infarction, multi-vessel lesion, high neutrophil, high hs-CRP, long vascular opening time and history of hypertension can increase the possibility for patients with preserved systolic function of left ventricle of heart failure after PCI, and can reduce the incidence of it after PCI.
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Received: 06 September 2015
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Corresponding Authors:
JIANG Ting-bo, E-mail:szjtb@medmail.com.cn
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[1] Steg PG ,Dabbous OH ,Feldman LJ,et al. Determinants and prognos tic impact of heart failure complicating acute coronary syn⁃dromes: observations from the Global Registry of Acute Coronary Events (GRACE)[J]. Circulation,2004,109(4):494-499.
[2] Bahit MC,Lopes RD,Clare RM,et al. Heart Failure complicating non- ST- segment elevation acute coronary syndrome: timing,predictors,and clinical outcomes[J]. JACC Heart Fail ,2013,1(3):223-229.
[3] 盖鲁粤,李雪梅,智光,等. 急性心肌梗死长期随访结果——预后影响因素的分析[J]. 中华心血管病杂志,2001,29(12):736-740.
[4] Wu AH,Parsons L,Every NR,et al. Hospital outcomes in patients presenting with congestive heart failure complicating acute myocardial infarction: a report from the Second National Registry of Myo⁃cardial Infarction (NRMI- 2) [J]. J Am Coll Cardiol,2002,40(8):1389-1394.
[5] Richards AM,Nicholls MG,Troughton RW,et al. Antecedent hypertension and heart failure after myocardial infarction[J]. J Am Coll Cardiol,2002,39(7):1182-1188.
[6] Giannuzzi P,Temporelli PL,Bosimini E,et al. Heterogeneity of left ventricular remodeling after acute myocardial infarction: results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infar⁃to Miocardico-3 Echo Substudy[J]. Am Heart J,2001,141(1):131-138.
[7] Yancy CW,Jessup M,Bozkurt B,et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines[J]. J Am Coll Cardiol,2013,62 (16):e147-239.
[8] Kolh P,Windecker S,Alfonso F,et al. 2014 ESC/EACTS Guidelines on myocardial revascularization[J]. Eur J Cardiothorac Surg,2014,46(4):517-592.
[9] White HD,Cross DB,Elliott JM,et al. Long-term prognostic importance of patency of the infarct- related coronary artery after thrombolytic therapy for acute myocardial infarction[J]. Circulation,1994,89(1):61-67.
[10] Pizzetti F,Turazza FM,Franzosi MG,et al. Incidence and prog⁃nostic significance of atrial fibrillation in acute myocardial infarction: the GISSI-3 data[J]. Heart,2001,86(5):527-532.
[11] Celik S,Erdöl C,Baykan M,et al. Relation between paroxysmal atrial fibrillation and left ventricular diastolic function in patients withacute myocardial infarction[J]. Am J Cardiol,2001,88(2):160-162,A5.
[12] Suleiman M,Khatib R,Agmon Y,et al. Early inflammation and risk of long-term development of heart failure and mortality in survivors of acute myocardial infarction predictive role of C-reactive protein[J]. J Am Coll Cardiol,2006,47(5):962-968.
[13] Anand IS,Latini R ,Florea VG,et al. C-reactive protein in heart failure: prognostic value and the effect of valsartan[J]. Circulation,2005,112(10):1428-1434. |
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