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| Clinical observation of the value of short time high frequency oscillation ventilation ( HFOV) improving the oxygenation of severe cases of human infections with Avian Influenza A (H7N9) who were complicated by acute respiratory distress syndrome(ARDS) |
| LIU Chao, GUO Qiang, WANG Jia - jia, ZHAO Da - guo, LIU Sheng - lan, JIN Jun, LU Shi - qi, HUANG Jian - an |
| Department of Critical Care Medicine, the First Affiliated Hospital of Soochow University, Suzhou 215006, China |
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Abstract Objective To investigate the value of high frequency oscillation ventilation(HFOV) improving the oxygenation of severe cases of human infections with Avian Influenza A (H7 N9 ) who were complicated by acute respiratory distress syndrome( ARDS). Methods Retrospective analysis severe cases infectived by Avian Influenza A ( H7 N9 ) (6 cases) who were complicated by acute respiratory distresssyndrome(ARDS) between march 2013 to March 2014. the oxygenation index of them was small than 300 mm Hg, everyone accepted mechanical ventilation treatment with low tidal volume and positive end - expiratory pressure,and accepted HFOV for 2 hours during mechanical ventilation. arterial blood samples were collected reaspectively at 0 min,30 min,120 min after HFOV. calculate the oxygenation index of every time point. Result the oxygenation index at 120 min(263. 17 ± 66. 39) mm Hg after HFOV was larger than which in 30 min(182. 17 ± 36. 44) mm Hg( P < 0. 05) which lager the 0 min (119. 00 ± 27. 24) mm Hg ( P < 0. 05). Conclusion Short time (2 hours) HFOV can improve the oxygenation of severe cases of human infections with Avian Influenza A (H7 N9 ) who were complicated by acute respiratory distress syndrome(ARDS).
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Received: 16 August 2015
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Corresponding Authors:
GUO Qiang, E - mail: ggqq7910@ 163. com
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Zhongguancun, 