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Clinical observation on the treatment of cerebral hemorrhage complicated with hyponatremia by CRRT |
Duan Yu-zhu, Zhao Qun-yuan, Chen An-bao, Yang Chun-yan, Yang Jian-hua, Wen Jing |
Department of Emergency, the Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China |
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Abstract Objective: To investigate the clinical effect and prognosis of cerebral hemorrhage complicated with hyponatremia after continuous renal replacement therapy (CRRT) treatment. Methods: 57 cases of cerebral hemorrhage complicated with hyponatremia from March 2014 to May 2015 in our hospital were enrolled in the study, and were divided into 2 groups randomly. Patients in the control group received routine medical treatment, while the patients in the observation group received CRRT. After the end of treatment, serum sodium level, urea nitrogen (BUN) and creatinine (SCr) were detected in patients by automatic biochemical analyzer, and the vital signs were also detected. Results: Observation group mortality rate was 3.45%, the control group was 28.57%, which was significantly higher than that in the observation group(P<0.01). After CRRT treatment, the serum sodium ion, BUN and SCr levels were lower than those before treatment in the observation group(P<0.05). After treatment, the serum sodium ion, BUN and SCr levels in the observation group were lower than those in the control group(P<0.05). Heart rate and mean arterial pressure were not significantly different compared with before treatment(P>0.05). Conclusion: On the basis of conventional medical treatment, CRRT treatment of cerebral hemorrhage complicated with hyponatremia can effectively correct the electrolyte disturbance, and improve renal function and prognosis.
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Received: 09 January 2017
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Corresponding Authors:
Zhao Qun-yuan, E-mail: E-mail:zhaoqunyuan@126.com
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