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| New progress in pathogenesis and treatment of hepatic injury with sepsis |
| Guan Jian-hui, Yi Zhao-quan |
| Intensive Care Unit, Xiangtan Hospital Affiliated to Nanhua University,Xiangtan 411100,China |
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Abstract Sepsis is one of the common causes of death in intensive care units. Recent studies have shown that there has been some progress in the clinical treatment of sepsis, but the morbidity and mortality of sepsis remains high. Sepsis is associated with microvascular dysfunction, which in turn leads to organ failure, and the pathogenesis of inflammatory and organ damage that leads to death in sepsis is currently not fully understood. It is currently believed that sepsis liver injury is a liver injury caused by factors such as inflammation and immunosuppression mediated by the immune response of patients with sepsis, and even leads to liver failure in severe cases. In this regard, prevention and treatment of liver damage and recovery of liver function are important ways to reduce the morbidity and mortality of patients with sepsis liver injury. Therefore, the understanding of the relevant body reaction mechanism of sepsis liver injury is particularly important.
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Corresponding Authors:
Yi Zhao-quan， E-mail: bingbing20110127@aliyun.com
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