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| Predictive value of mean platelet volume/platelet count for acute ST-elevation myocardial infarction with PCI |
| Li Yan-qiu, Chen Guang-sheng, Ma De-yuan, Jia Zhong-rui |
| Department of Emergency, the First People′s Hospital of Xining, Xining 810001, China |
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Abstract Objective To investigate the predictive value of mean platelet volume/platelet count(MPV/PC) for acute ST-elevation myocardial infarction with PCI. Methods In this retrospective study, a total of 244 consecutive patients with ST-elevation myocardial infarction were eligible to be enrolled from December, 2015 to December, 2017. According to the admission mean platelet volume/platelet count values, the population was divided into two groups: high mean platelet volume/platelet count group (n=122, MPV/PC>0.048) and low mean platelet volume/platelet count group (n=122, MPV/PC<0.048), using Cox model multivariate analysis. Results Multivariate analysis showed that high MPV/PC was an independent predictor of major adverse cardiovascular event (MACE，HR1.182, 95%CI1.033-1.332, P=0.003), cardiovascular mortality(HR1.105, 95%CI1.024-1.189, P=0.020),nonfatal myocardial reinfarction (HR1.233, 95%CI 1.127-1.340, P=0.009), unplanned repeat revascularization (HR1.080, 95%CI1.012-1.149, P＜0.001), and heart failure (HR 1.162,95%CI1.081-1.245, P=0.014), achievement of TIMI 3 flow (HR1.623, 95%CI1.571-1.706, P=0.033), respectively. Conclusion Mean platelet volume/platelet count ratio is able to predict long-term adverse outcomes in patients with STEMI undergoing PCI.
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Corresponding Authors:
Jia Zhong-rui, E-mail: 15990927@qq.com
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| ［1］Tian C, Song J, He D, et al.Predictive Value of Mean Platelet Volume/Platelet Count for Prognosis in Acute Myocardial Infarction［J］.Int Heart J, 2018, 59(2):286-292.
［2］何宝强，李晓梅.急性心肌梗死患者平均血小板体积变化的意义［J］.心血管病学进展， 2018, 39(2):235-238.
［3］王静，谷云飞，金军，等.平均血小板体积/血小板计数比值对急性 ST 段抬高型心肌梗死 PCI 术后院内心脏不良事件的预测作用［J］.中国心血管病研究， 2016， 14(1)：45-48.
［4］汪洋，李彩荣，王宁夫.平均血小板容积和Gensini积分对急性ST段抬高型心肌梗死患者PCI术后预后的影响［J］.临床和实验医学杂志， 2018， 17(6)：602-604.
［5］辛慧慧，李屹，白睿，等.血小板参数对年轻男性STEMI患者发病的预测作用［J］.武警医学， 2018， 29(1)：5-6,9.
［6］鲁津津，夏勇.血小板指标与冠心病患者冠状动脉病变程度相关性研究［J］.检验医学与临床， 2018, 15(7):1009-1011.
［7］Huczek Z, Kochman J, Filipiak KJ, et al. Mean platelet volume on admission predicts impaired reperfusion and long-term mortality in acute myocardial infarction treated with primary percutaneous coronary intervention［J］. J Am Coll Cardiol, 2005, 46(2): 284-290.
［8］龚超.血小板参数对急性心肌梗死患者生存状况的影响［J］. 现代实用医学， 2018， 30(3)：316-318.
［9］O′Brien JR.A relationship between platelet volume and platelet number［J］. Thromb Diath Haemorrh, 1974, 31（2）:363-365.
［10］李瑞娜，李红，李博. 血小板分布宽度与急性心肌梗死患者严重程度及预后的相关性分析［J］.中国急救医学， 2018, 38（5）: 399-402. |
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