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| Role of oxidative stress in organ dysfunction of sepsis |
| Wang Xing-cheng, Yang Lei, Wen Xiao-xiong, Wang Bin-sheng, Peng Chao, Chai Chen |
| Department of General Surgery, First Affiliated Hospital of Lanzhou University, Lanzhou 730000, China |
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Abstract Sepsis is a life-threatening organ dysfunction caused by the host′s imbalance of response to infection. It is a serious complication of clinical critical patients. Sepsis can progress to severe sepsis, and septic shock eventually leads to death. Various mechanisms are involved in the occurrence and development of sepsis. Oxidative stress, as a major cause of sepsis and septic shock, has been paid more and more attention in recent years. This article reviews the mechanism of oxidative stress in the damage of human organ function in sepsis.
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Corresponding Authors:
Chai Chen, E-mail: chasechai@126.com
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