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| Studies on risk factors associated with death from infective endocarditis surgery |
| He Ji-gang, Li Yong-wu, Gui Long-sheng, Yan Dan, Zhao Wei |
| Department of Cardiovascular Surgery, First People′s Hospital of Yunnan Province, Kunming 650032, China |
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Abstract Objective To explore the death-related risk factors associated with infective endocarditis surgery. Methods A total of 80 infective endocarditis patients admitted to the First People′s Hospital of Yunnan Province from January 2008 to January 2018 were selected, and according to surgical results were divided into successful group (n=60) and postoperative death group (n=20). The retrospective study method was adopted. Basic information of the two groups of patients were collected included gender, age, presence of peripheral vascular disease, smoking, requirement for chest surgery, and presence of abdominal pain, chest pain, nausea, hypotension. Laboratory test results and also collected. Results Finally, 80 patients with infective endocarditis were enrolled, including 60 patients (75%) in the successful group and 20 patients (25%) in the postoperative death group. The age of the two groups (46.2±0.3 in the successful group, 51.3±1.9 in the postoperative death group, P=0.013), chest pain (18.3% in the successful group, 90% in the postoperative death group, P=0.000), abdominal pain (8.3% in the successful group, 55% in postoperative death group, P=0.000), hypotension (3.3% in the successful group, 75% in postoperative death group, P=0.000) and platelet value (located at 60×109 /L0.05). Univariate Logistic regression analysis showed age (B=-0.0441, P=0.0021), chest pain (B=-0.0321, P=0.0000), abdominal pain (B=-0.0125,P=0.0311), and hypotension (B=-0.2818,P=0.0312), platelet values (B=-0.1631, P=0.0025), and the time to stop (B=-0.2513, P=0.0000) were independently associated with death. Conclusion Infective endocarditis the patient is older than 60 years old, preoperative chest pain, abdominal pain and hypotension, low preoperative platelet count, and may increase the risk of surgical death.
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Corresponding Authors:
Zhao Wei, E-mail: zhaowei123@163.com
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