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| The effect of Live Combined Bifidobacterium and Lactobacillus Tablets and probiotic yogurt on lipid metabolism in critical patients |
| LIU Rui-fang, CHENG Qing- hong, LI Jian- hua, LIU Ying,PENG Chong, XI Ying-bo |
| Department of Critical Care Medicine, the First Affiliated Hospital of Medical College, Shihezi University, Shihezi 832002, China |
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Abstract Objective To explore the effect of Live Combined Bifidobacterium and Lactobacillus Tablets（Jin Shuangqi）and probiotic yoghurt supplementation on lipid profile in critically ill patients, as well as to study interaction effects of Jin Shuangqi and probiotic yoghurt existing or not. Methods Sixty critically ill patients were randomly divided into four groups: A, control group（n＝15）; B, Jin Shuangqi group（n＝15）; C, probiotic yoghurt group（n＝15）; D, combination group（n＝15）. Triglyceride（TG）, total cholesterol（TC）, high-density lipoprotein cholesterol（HDL-C）, low density lipoprotein cholesterol （LDL-C）as well as total cholesterol levels: HDL-C ratio and LDL-C: HDL-C ratio were adopted as the observation indexes on day 14, to conduct a two-factor（Jin Shuangqi, probiotic yoghurt）2×2 factorial design. Results On day 14, the levels of TG, LDL-C and HDL-C as well as TC/HDL-C, LDL-C/HDL-C were statistically different in the four groups（P＜0.05）. Factorial design showed the levels of TG and HDL-C were significant different（P＜0.05）according to Jin Shuangqi adding or not; the levels of TG, LDL-C, HDL-C and total cholesterol levels: HDL-C ratio, LDL-C: HDL-C ratio, were significantly different（P＜0.05）according to probiotic yoghurt adding or not. Jin Shuangqi and probiotic yoghurt work interactively for TG（F＝4.64, P＜0.05）. Conclusion Jin Shuangqi and probiotic yoghurt could improve the blood lipid level of critically ill patients, which is beneficial to the recovery and prognosis.
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Received: 24 March 2016
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Corresponding Authors:
CHENG Qing-hong, E-mail: xunfeicheng@aliyun.com
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