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| Monitoring central venous blood oxygen saturation for risk stratification of sepsis |
| Hao Ming-wei,Zhang Lin, Zhang Che-ming, Peng Song, Zhong Ming-mei, Mo Bao-ding |
| Hao Ming-wei, E-mail: zhengdingbin@sina.com |
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Abstract Objective This study aims to investigate the change of central venous blood oxygen saturation（ScvO2）in predicting the prognosis in the patients with sepsis. Methods We collected the information of 109 septic cases admission of our hospital. The ScvO2 and alveolar- arterial oxygen （PaO2）on admission and 6 h, 24 h, 48 h after that were measured. The patients were groups based on the worst index of acute physiology and chronic health score（APACHEⅡ assessment）within 24 h of ad⁃ mission, and their relative clinical information was compared. Logistic regression was used to analyze the risk factors that affect the prognosis of patients with sepsis. Results Comparing with normal group pa⁃ tients, APACHEⅡ score, MODS incidence and morbidity were increased in ScvO2 low group with statis⁃ tical significance（P＜0.05）; in the patients with ScvO2 decreased and ScvO2＞70% after the full recov⁃ ery treatment 6 h after admission, incidence and morbidity of MODS declined compared with ScvO2 low than standard, and the difference had statistical significance（P＜0.05）. Outcome of Logistic regression revealed that APACHE Ⅱscore, abnormal of creatinine, adequate fluid resuscitation 6 h after admission, ScvO2＜70% were independent risk factors of patients' prognosis. Conclusion Early ScvO2 could be the important index of severity in judging condition of patients with sepsis. ScvO2＞70% 6 h after admis⁃ sion or not has important meaning in assessing the prognosis of sepsis patients.
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Received: 08 June 2016
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