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| Correlation study between red blood cell distribution width and prognosis of patients with severe pneumonia |
| Liu Jing-jing, Pei Xue-yong, Zhong Kang |
| Department of Respiratory Medicine, Maanshan People′s Hospital, Maanshan 243000, China |
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Abstract Objective To investigate the correlation between red blood cell distribution width(RDW) and prognosis of patients with severe pneumonia, and to investigate the value in assessment of prognosis in severe pneumonia patients. Methods The clinical data of 144 patients with severe pneumonia admitted to the Department of Respiratory and Critical Care Medicine of Maanshan People′s Hospital from January 2013 to June 2016 were retrospectively analyzed. We retrospectively collected the patients′ data, including RDW and procalcitonin(PCT) within the twenty four hours after admission, mechanical ventilation, and length of hospitalization, and then evaluated the APACHEⅡ score. The patients were divided into death group and survival group based on their hospital outcomes. The differences of RDW, PCT and APACHEⅡ between the two groups were compared. According to the RDW, The patients were divided into the RDW normal group(11.6%～14.4%) and the increased group(>14.4%). Two groups′ PCT and APACHEⅡ were compared. The relationships between RDW, PCT and APACHEⅡ score were analyzed by pearson correlation analysis. Receiver operating characteristic(ROC) curve was plotted to assess the prognostic value RDW, PCT and APACHEⅡ for prognosis of severe pneumonia patients. Results RDW, PCT, APACHEⅡ scores and mechanical ventilation time were significantly higher in the death group than in the surviving group(P＜0.05); Length of hospitalization was of no significant difference between the two groups(P＞0.05). RDW, APACHEⅡ score and mechanical ventilation time were significantly higher in the RDW increased group(P＜0.05). PCT and length of hospitalization were of no significant difference between the two groups(P＞0.05); RDW was significantly and positively correlated with APACHEⅡ(r=0.51, P＜0.01); The area under the ROC curve(AUC) of RDW for prognosis was 0.945(95% CI 0.907～0.982); AUC of RDW for prognosis was 0.948(95% CI 0.913～0.982). Conclusion RDW can be a good indicator of the severity of severe pneumonia and the prognosis of severe pneumonia.
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Received: 03 January 2017
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